I could only think of four famous Wilmas -- and only one of them is a real human being.
The human being: Wilma Rudolph, Olympic Gold Medalist sprinter.
The cartoon: Wilma Flintstone, of course.
The science-fiction heroine: Wilma Deering (from Buck Rogers), below as played by Erin Grey
The hurricane: Wilma (2005)
Anyone (or anything) else?