Discover magazine's blog takes on this stimulating subject.
Coffee: A Most Enigmatic, Ubiquitous Beverage
Sounds like it's mostly a good thing.
"Two umbrella reviews were published last year (here and here), and their findings flew in the face of centuries of coffee gossip. The verdict was that coffee drinking is linked to lowered risk of myriad diseases like type 2 diabetes, heart disease, a few types of cancer, liver disease, Parkinson’s, Alzheimer’s and depression—not too shabby.
Above all, coffee drinkers were less likely to die early from any cause. And with the possible exception of drinking it while pregnant, there were no negative effects to speak of. “The key message is that with the evidence that we have up to date, we can say that coffee can be part of a healthy diet,” says nutritional epidemiologist Giuseppe Grosse at the University of Catania in Italy and lead author of one of the umbrella reviews."
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