Just when you thought vaccines in the USA were being phased out (and under the idiocy of RFK Jr.'s leadership of our national health structure, that could still happen) -- we get a great story about a form of a vaccine for whooping cough that can be administered via the nose.
Well, it's an advance.
Nasal Vaccine Blocks Whooping Cough Spread and Infection
This strategy could transform both whooping cough prevention and the broader market for respiratory bacterial vaccines.The first three paragraphs sum it up pretty well; the rest is details.
"In a landmark study published in Nature Microbiology, the team demonstrated that their nasally-delivered, antibiotic-inactivated Bordetella pertussis (AIBP) vaccine not only prevents severe disease but also curbs bacterial transmission — an achievement long sought by vaccine developers worldwide.
The work, led by Professor Kingston Mills and Dr Davoud Jazayeri of Trinity’s School of Biochemistry and Immunology, introduces a needle-free mucosal vaccine platform capable of inducing durable local immunity directly at the infection site.
This strategy could transform both whooping cough prevention and the broader market for respiratory bacterial vaccines, addressing an urgent global need for next-generation immunisation technologies."
Reference: Jazayeri SD, Borkner L, Sutton CE, Mills KHG. Respiratory immunization using antibiotic-inactivated Bordetella pertussis confers T cell-mediated protection against nasal infection in mice. Nature Microbiology, 2025:1-13. doi: 10.1038/s41564-025-02166-6
So there's a global need, but the USA is going to be left out of it, apparently.
Idiocy.
BTW, in 2024, whooping cough cases hit their highest numbers in a decade.
So not being part of a great advance for preventing and treating it?
That's REAL idiocy.

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