Sunday, January 11, 2026

Not skinsane

 

Sorry, this one wrote itself.

Common Acne Drug Linked to Lower Schizophrenia Risk


I recommend reading the article to get the background, especially about excessive synaptic pruning, which is implicated in the development of schizophrenia. Here's the takeaway:

"The finding aligns with research linking neuroinflammation and abnormal synaptic pruning to schizophrenia, suggesting that modifying inflammatory processes early in life could help protect the brain. Since doxycycline is already widely prescribed and well understood, it presents a realistic starting point for exploring preventive strategies in psychiatry."

Reference: Lång U, Metsälä J, Ramsay H, et al. Doxycycline use in adolescent psychiatric patients and risk of schizophrenia: an emulated target trial. Am J Psychiatry. 2025. doi: 10.1176/appi.ajp.20240958



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