Vaccinations work, episode 1

 

Just a warning, I may have more posts like this.

Vaccination During Pregnancy Protects Newborns From Whooping Cough

"A research team under the auspices of Prof. Beate Kampmann, Director of the Institute of International Health at Charité and Scientific Director of the Charité Center for Global Health, has now been able to prove for the first time that the antibodies transmitted by the mother are not only present in the blood but also in the nasal mucosa of newborns – which is precisely where the pathogens enter the body. "We knew that maternal antibodies are passed on by way of the placenta. We were surprised, however, to find that we could also detect them in the nasal mucosa of newborns – in a manner that is gentle on the children. This underlines the effectiveness of indirect vaccination"

"Even today, whooping cough remains a deadly disease in many parts of the world. Every year, between 200,000 and 300,000 people die from it, mainly young children in low- and middle-income countries where good vaccines are not always available. Consequently, the research team is planning further studies to help improve existing pertussis vaccines and test the efficacy of new vaccines."

 REFERENCE: 

Saso A, Fröberg J, Jobe H, et al. Mucosal immune responses to Bordetella pertussis in Gambian infants after maternal and primary vaccination: an immunological substudy of a single-centre, randomised, controlled, double-blind, phase 4 trial. Lancet Microbe. doi: 10.1016/j.lanmic.2025.101219