Urbana, Illinois, was named after Urbana, Ohio, which was named after Urbanna, Virginia. Urbanus means city dweller and was the name of eight Popes. But: Urbanna, Virginia means "City of Anne" and was named after Queen Anne of England.
(This question occurred to me because I noticed Maryland has a town named Urbana.)
And there's one in Venezuela. I imagine that had something to do with honoring a Pope.